PhD-Defence-by-Stephanie-Ingemann-Bisgaard

"The prevalence of allergies is increasing worldwide and is a global burden for the healthcare sector, with the skin prick test (SPT) being a common method for allergy screening. The aim of the InstaPatch project, which this PhD thesis is a part of, was to improve on the SPT and develop a novel test for fast and quantitative allergy diagnostics in the skin. The InstaPatch is envisioned as an intradermal electrochemical biosensor based on microneedles (MNs) which are sub-mm structures that act like small needles piercing the skin. The aim of this PhD project was to ensure the mechanical stability of the MNs, investigate coating methods for allergen delivery, and perform in vivo experiments of allergen delivery."

Principal supervisor: Professor Stephan Sylvest Keller, DTU Nanolab
Co-supervisor: Senior researcher Katrine Lindholm Bøgh, DTU Food

Examiners:
Associate Professor Line Hagner Nielsen, DTU Sund
Professor Urs Otto Häfeli, Pharmaceutical Sciences, UBC
Professor Per Stahl Skov, SDU & Head of Reflab Aps

Chairperson at defence: Associate Professor Paul Kempen